Melanoma
In the melanoma program, VacciZone is designing a specific variant of ASC speck that carries a part of MAGE-A1 antigen, called tMageA1-ASC. This fusion protein can form the speck structure and be purified. A cancer model will be created on C57BL/6 mice by injecting B16F10 cells in order to grow tumor tissue. tMageA1-ASC specks will be injected into the tumor tissue in order to target immune cells.