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Currently ongoing projects and progress information on Vaccizone’s vaccine development platform driven by ASC Technology.

Covid 19

In the Covid-19 program, VacciZone is designing a specific variant of ASC speck carrying antigens coming from the Spike protein of SARS-CoV2. We have demonstrated that our fusion protein can form a functional speck structure. The purified specks have been injected into the BALB/C mice. The collected sera from immunized mice showed that the Vaccizone Covid-19 vaccine stimulates the expected immune response against SARS-CoV2. Phase-I studies are expected to start soon.

Melanoma

In the melanoma program, VacciZone is designing a specific variant of ASC speck that carries a part of MAGE-A1 antigen, called tMageA1-ASC. This fusion protein can form the speck structure and be purified. A cancer model will be created on C57BL/6 mice by injecting B16F10 cells in order to grow tumor tissue. tMageA1-ASC specks will be injected into the tumor tissue in order to target immune cells.

Veterinary

In the veterinary vaccines program, VacciZone is utilizing ASC Speck technology to create powerful purely protein-based alternatives to existing veterinary vaccines resistant to harsh weather conditions.